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Frontiers | The mechanisms crosstalk and therapeutic opportunities between ferroptosis and ovary diseases

These triggers can create a “cascade” that both represents and results in clinical manifestations and symptoms

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they act as essential signaling molecules regulating vital physiological processes such as cell proliferation, differentiation and apoptosis [2], However, at pathologically high levels, ROSs can contribute to the development of diseases such as cancer, pulmonary disease and cardiac disorders [2,3,4]

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