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Meanwhile, the melanin content in the vehicle control group (1.188 ± 0.091 µ g/mg of skin) showed no significant difference as compared with that in the L-glutathione treatment group (1.122 ± 0.056 µ g/mg of skin)

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Another important mechanism of action of NAC is its influence on the function of synovial fibroblasts, which, in RA, exhibit an aggressive phenotype and contribute to joint destruction through excessive production of MMPs