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In the BiNPs-NISM-Dox/Pi3Ki@BSA group, the survival rate was reduced compared to conditions without X-irradiation, highlighting the radiosensitizing and chemosensitizing roles of Pi3K pathway inhibition in GBM models, as established in studies where Pi3K blockade increases tumor sensitivity to DNA-damaging 104,105

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Compared to untargeted ubiquinone analogs, MitoQ10 demonstrates a superior potential to accumulate in the mitochondria up to 1000 folds