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Traditionally, in PCOS, one of the main aspects to consider is hyperglycemia, as it can trigger type 2 diabetes mellitus, cardiovascular diseases, the production of inflam-matory factors, and reactive oxygen species that cause oxidative stress and tissue damage 5
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This proved GLP-1 analogue, exenatide, to have cardioprotective properties, where one of the underlying mechanisms is oxidative stress reduction
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