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Whereas in tissue culture conditions almost all cysteine is oxidized to cystine within minutes, in transgenic mice lacking the substrate-specific subunit of the cystine-glutamate amino acid transporter xCT (aka SLC7A11), there are substantial amounts of cysteine present in plasma [222]
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Hydrogeologic units within the deeper basin are exposed in deeper canyons and at the edges of uplifts
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