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Based on the results obtained using inductively coupled plasma mass spectrometry, the skin permeability coefficients (Kp) for GHK-Cu over a 48-hour study ranged from 3 × 10 -7 cm/h across heat-separated epidermis to 5.5 × 10 -3 cm/h across isolated stratum corneum

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Possible laboratory measurements include collagen-associated markers, fibroblast behaviour, copper-enzyme activity, NAD+/NADH ratios, mitochondrial signals, ATP-related measurements and oxidative-stress indicators