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TLR and MAPK) (69), with downregulation of the pro-inflammatory cytokines TNFα and IL-1βand increased IL-10 production ( in vitro treatment of human monocyte-derived DCs with CO has been reported to block TLR3- and 4-induced phenotypic maturation and alloreactive T cell proliferation (70)

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These results further demonstrated that the fluorescence activation of the MnO 2 -nanoprobe was specific to target cells