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The available safety data from clinical trials suggest that retatrutide often causes gastrointestinal problems, such as nausea, diarrhea, vomiting, and constipation, and that some trial participants discontinue the drug, particularly at higher doses

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Briefly, images were converted to 8-bit images and scald to 0.366 microns per pixel (corresponding to 20× magnification on the Leica microscope)