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[48] Importantly, crystallographic data demonstrate that Zn‐bound‐SOD1 monomers and CCS‐Zn‐bound‐SOD1 heterodimers have a much lower affinity for lipid bilayers compared with CCS homodimers or apo‐SOD1 alone, [47] a factor not taken into account in recent studies of the ternary SOD1‐CCS‐(Cu + )‐Ctr1 complex

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2.2 Blood sampling and consent form On the day of AAV diagnosis, informed consent was obtained, AAV-specific indices were assessed, and whole blood was collected from patients with AAV