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It circulates at relatively high concentrations when you're young, around 200 ng/mL in your 20s , and drops steadily with age, reaching roughly 80 ng/mL by your 60s

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Brachial artery blood flow and vessel diameter were assessed using ultrasound at 1-hr prior to exercise (1hrPrEX), after each exercise bout, immediately post-exercise (immediate PEX), and 30 minutes post exercise (30minPEX) at visits 2 and 4