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Although the precise etiology remains elusive, genome-wide association studies have identified over 200 risk loci, particularly within the major histocompatibility complex region, underscoring the importance of immune dysregulation (Hauser and Cree, 2020)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 63.McFarthing K, Buff S, Rafaloff G, Fiske B, Mursaleen L, Fuest R, Wyse RK, Stott SRW