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Conclusion Glutathione Reductase Enzyme gives a Picture for damaged cells due to Oxidative stress during chronic inflammation in Patient with RA and Vitamin C can be considering as approved parameter for oxidative stress due to inflammation respond that will consume by Non- Enzymatic Anti-Oxidant effect

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Inflammatory by-products and oxidative stress can stimulate CGRP receptors, indicating their role as detectors of environmental oxidative states (32)