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Cellular response Epitalon activates telomerase to maintain telomere length at the ends of chromosomes, stimulates the pineal gland to restore melatonin production, and upregulates antioxidant enzymes, addressing aging at the DNA, hormonal, and oxidative-stress levels at once

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Briefly, 10 μl kidney homogenates (20 μg protein) were mixed with 39 μl PBS, 1 μl of 0.03% hydrogen peroxide (H 2 O 2 ), and 50 μl of 200 μM ADHP solution