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At the 3-5 year follow up mark, there was found to be 67% of increased risk of invasive colorectal adenomas or advancement of previous lesions, as well as a more than 2x increased risk of at least 3 colorectal adenomas and prostate cancer [3]
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Our study not only provides an explanation for the long-standing clinical observations of the correlation between increased vitamin B12 level and acne development, but also suggests a molecular mechanism for acne pathogenesis