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Epithalon Epithalon is a synthetic tetrapeptide based on the natural peptide Epithalamin produced by the pineal gland
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The activation of TBK1 enhances the binding of autophagy receptors, such as calcium binding and coiled-coil domain 2 (CALCOCO2) and optineurin (OPTN), to the ubiquitylated mitochondria, facilitating selective mitochondrial autophagy (Seabright et al., 2020)
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