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Humoral factors in ALS patients during disease progression | Journal of Neuroinflammation | Springer Nature Link

Furthermore, studies on serum from SZ patients showed elevated levels of polyamine oxidase (the enzyme responsible for degrading PAs) (96, 97), while the activities of three enzymes involved in PA synthesis—ornithine aminotransferase, antizyme inhibitor 1 (AZIN1), and ornithine cyclodeaminase —were found to be reduced in the prefrontal cortex of both treated and untreated patients (98), ultimately potentially leading to disrupted polyamine homeostasis

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Whey—the waste-stream that became more valuable than the food product