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Genes and Proteins involved in infection and pathogenesis Adaptation to the mammalian host When an Ixodes vector tick begins feeding on a mammalian host, there is a dramatic alteration in the tick midgut environment (see Radolf and Samuels, 2021)

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This structure revealed an elongated solenoid tightly bound to a ~60 Å long peptide, with importin β spanning ~110 Å (Fig