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The core strategy employs comprehensive, multi-pronged interventions such as microbiota-targeted interventions, herbal and multi-component pharmacological modulation, neural and neurochemical circuit regulation, metabolic and immune-inflammatory pathway modulation and chronobiological and circadian rhythm regulation, to achieve precise manipulation of the gut ecosystem
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However, chick embryos treated with rigid and flaccid paralysis (unloading) phenotypes (through treatment with decamethonium bromide or pancuronium bromide) have a decreased calcaneal tendon elastic modulus that corresponds to decreased LOX activity
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