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Give it time: Allow at least one full skin-cell cycle (about 4–6 weeks) to see changes

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Furthermore, the researchers observed that blood samples from patients with multiple sclerosis exhibited a higher frequency of IFN-γ + regulatory T cells compared to healthy controls, which in turn facilitated the expression of pro-inflammatory genes, including TBX21 , IFN-g , and HIF-1α (76) (77)