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Abstract The purpose of this study was to investigate the utility of plasma pharmacokinetic and pharmacodynamic measures including plasma deoxynucleosides, homocysteine and methylmalonic acid concentrations in understanding the time course and extent of the inhibition of thymidylate synthase (TS) by pemetrexed in the context of a phase I/II combination study with vinorelbine

Listing Number: D481234

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ClinicalTrials.gov No registered or completed human clinical trial for SLU-PP-332 as of June 2026