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9,15,53–55,58,63,68,69 The point estimates of the risk ratio indicated a higher risk in DPYD ∗2A carriers compared to wild-type patients in all studies, but the confidence intervals of three studies 15,53,55 also included the possibility of a lower risk in DPYD ∗2A carriers

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The nominator emphasized that therapeutic apheresis nurses' training and skill level are distinct from nurses collecting blood products from healthy donors