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Conversely, certain bacterial genera, including Alistipes , Barnesiella , and Gordonibacter , have shown negative correlations with gastrointestinal symptoms, suggesting potential protective roles [47]

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It is also notable that cystine withdrawal affects the extracellular and intracellular redox states, and that this could have contributed to the observed effects on cell viability in a manner distinct from erastin effects on cystine import