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In addition, it comprehensively examines the potential applications and challenges in targeting nonhistone lactylation modification in antitumor treatment

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The malignant Reed–Sternberg cells of cHL are characterized by the expression of CD30, a member of the tumor necrosis factor super-family, and given its restricted expression to a small proportion of activated B cells, T cells, and eosinophils, it represents an ideal target for monoclonal antibody therapy [69]