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Although long-term risks of sermorelin use are not known, it’s Medical emergency If you notice any of the following symptoms of a severe allergic reaction, call emergency medical services (911 in the United States) or go to the nearest emergency room: hives or other rashes swelling of the mouth, tongue, lips, or face shortness of breath tightness in the chest Side effects The most common side effect of sermorelin is caused by its injection under your skin