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We performed de novo resistance studies with HCV replicons and NGS analysis of samples from BEM monotherapy clinical studies (NCT03219957) to establish BEM’s resistance profile

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Pairing these observations with ongoing research studying metal-binding peptides such as the Amino Terminal Copper and Nickel (ATCUN) motifs, which sequester metal ions in physiological environments, has confirmed these chelating agents as important adjuvants to traditional antibiotic treatments