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National Cancer Institute 60 cell line screening (NCI-60) TC-1 (NSC: 843989), TC-Thio (NSC: 843990), and TC-Py (NSC: 843991) were submitted to the U.S

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804 Practical challenges in the epigenetic drug development and application Massive efforts have been made in epigenetics-targeting drug development, whether approved in different countries for the treatment of specific indications or currently identified and further evaluated in fundamental experiments or clinical trials, exhibiting notable potential