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Methylfolate will not support this job—folinic acid will.† Hair loss or slow wound healing : Rapidly dividing cells need DNA synthesis support.† Low red blood cell count : Blood cell production depends on DNA synthesis.³⁸† Children with cerebral folate deficiency : 58–76% of neurodivergent children test positive for folate receptor autoantibodies

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After binding CRHR1, CRH initiates a cascade of intracellular signalling which leads to the release of ACTH from the anterior pituitary