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Synthesis From the starting material phenol, paracetamol can be made in the following manner: Phenol is nitrated using sulfuric acid and sodium nitrate (as phenol is highly activated, its nitration requires very mild conditions compared to the oleum-fuming nitric acid mixture required to nitrate benzene)

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5.2 Mitochondria-targeted antioxidants The targeted mitochondrial antioxidant mitoquinone (MitoQ) has demonstrated protective effects in AKI by attenuating OS and apoptosis

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