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169 In another postmortem study, it was found that the coverage of blood vessels by AQP4-positive astrocyte terminals was reduced in the OFC of MDD patients

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These catecholamines can be polymerized by light in the presence of oxygen, resulting in a certain type of melanin.‍ (18–20) Although melanin absorbs UV light and protects the skin against DNA damage induced by UV irradiation, it also acts as a photosensitizer, generating reactive oxygen species including superoxide anion radicals and singlet oxygen, and also hydroxyl radicals in the presence of metal-ions.‍ (21) Pyruvic acid markedly decreased the dG concentration